Hierarchical Global Pointer Network: An Implicit Relation Inference Method for Gene-Disease Knowledge Discovery
نویسندگان
چکیده
The investigation of new associations between genes and diseases is a crucial knowledge extraction task for drug discovery. In this paper, we present novel approach to gene-disease discovery in the 8th China Health Information Processing Conference (CHIP 2022) [31] Open Shared Task AGAC Track ( http://www.cips-chip.org.cn/2022/eval1 ). Selective annotation latent topic are two major challenges task. To address these challenges, propose Hierarchical Global Pointer Network with propagation module extract implicit relations that inferred based on explicit relations. We also first one design unified end-to-end model which can achieve three tasks simultaneously alleviate problem selective annotation. experiment results show method proposed F1-scores 52%, 31% 30% respectively.
منابع مشابه
Knowledge discovery based on an implicit and explicit conceptual network
s (whole text collection), and κ is a slope constant set to 0.2. df(q) is the number of abstracts including q and N is the total number of documents (whole text collection). tf(q|d) is
متن کاملDesigning an Ontology for Knowledge Discovery in Iran’s Vaccine
Ontology is a requirement engineering product and the key to knowledge discovery. It includes the terminology to describe a set of facts, assumptions, and relations with which the detailed meanings of vocabularies among communities can be determined. This is a qualitative content analysis research. This study has made use of ontology for the first time to discover the knowledge of vaccine in Ir...
متن کاملDiscovering Implicit Entity Relation with the Gene-Citation-Gene Network
In this paper, we apply the entitymetrics model to our constructed Gene-Citation-Gene (GCG) network. Based on the premise there is a hidden, but plausible, relationship between an entity in one article and an entity in its citing article, we constructed a GCG network of gene pairs implicitly connected through citation. We compare the performance of this GCG network to a gene-gene (GG) network c...
متن کاملWeighted-HR: An Improved Hierarchical Grid Resource Discovery
Grid computing environments include heterogeneous resources shared by a large number of computers to handle the data and process intensive applications. In these environments, the required resources must be accessible for Grid applications on demand, which makes the resource discovery as a critical service. In recent years, various techniques are proposed to index and discover the Grid resource...
متن کاملBiomarker Gene Signature Discovery Integrating Network Knowledge
Discovery of prognostic and diagnostic biomarker gene signatures for diseases, such as cancer, is seen as a major step towards a better personalized medicine. During the last decade various methods, mainly coming from the machine learning or statistical domain, have been proposed for that purpose. However, one important obstacle for making gene signatures a standard tool in clinical diagnosis i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Communications in computer and information science
سال: 2023
ISSN: ['1865-0937', '1865-0929']
DOI: https://doi.org/10.1007/978-981-99-4826-0_2